You can exclude a site from backups of a SharePoint Online app. Excluding a site does not remove that site from the app, but the site is not backed up.
Procedure
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From the navigation pane, go to Protect > Office 365.
The Office 365 Overview page appears.
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On the Apps tab, click the app.
The Overview page of the app appears.
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On the Sites tab, in the row for the site that you want to exclude, click the action button , and then click Manage > Exclude from backup.
A confirmation dialog box appears.
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Click Yes.